Perspective Therapeutics

Radiochemist

Coralville, IA
Full Time
Isotope Manufacturing
Manager/Supervisor

Objective

We are seeking an experienced and motivated Radiochemist to join our dynamic team. The successful candidate will be responsible for the development of radiolabeling, purification, and characterization methods for various compounds for use in preclinical and clinical studies. This role will involve close collaboration with multidisciplinary teams, including biologists, pharmacologists, and clinicians, to support the development of our radiopharmaceutical products.

Essential Functions

  • Synthesis of Radiolabeled Compounds: Design, synthesize, and optimize radiolabeling methods of compounds (e.g., PET, SPECT, and alpha emitting isotopes) for use in preclinical and clinical studies.
  • Radiochemical Purity and Quality Control: Perform and develop analytical methods to ensure the radiochemical purity, stability, and quality of radiolabeled compounds. Contribute to the development of critical quality attributes of various products.
  • Process Development: Contribute to the development and optimization of radiolabeling processes through identification of critical process parameters, including scale-up for clinical production.
  • Regulatory Compliance: Ensure all radiochemical activities comply with relevant regulations, including GMP, GLP, and safety protocols.
  • Documentation: Maintain accurate records of all experiments, procedures, and results. Prepare technical reports and contribute to regulatory submissions.
  • Cross-Functional Collaboration: Work closely with other departments, including Manufacturing, Pharmacology, and Clinical Development, to support the integration of radiochemistry into the drug development process.
  • Safety: Uphold strict safety standards in handling radioactive materials, and participate in the maintenance of radiation safety procedures and protocols.
  • Innovation: Stay abreast of the latest advancements in radiochemistry and radiopharmaceutical development, and apply this knowledge to drive innovation within the company.

Qualifications

To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed below are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Education / Experience

  • Education: Ph.D. in Radiochemistry, Chemistry, or a related field. Exceptional candidates with a Master’s degree and significant experience will also be considered.
  • Experience: 3+ years of experience in radiochemistry, preferably in a pharmaceutical or clinical research environment.
  • Proficiency in the synthesis and handling of radioactive isotopes (e.g., Pb-203, Pb-212, Ga-68, Cu-64, Cu-67 and F-18).
  • Strong background in analytical techniques such as HPLC, TLC, GC, NMR, and mass spectrometry.
  • Experience with automated radiochemistry synthesis modules is a plus.
  • Thorough understanding of radiopharmaceutical development, including regulatory requirements for use of products in clinical trials (e.g., 21CFR Part 211, 21CFR Part 212, etc.).
Knowledge / Skill / Ability
  • Deep understanding of radiochemistry techniques related to the radiolabeling of molecules and their purification
  • Knowledge of radioactive decay, RAM transportation regulations and international shipments
  • Effective communication, including writing, speaking and interpersonal communication.
  • Rapid critical thinking and problem-solving abilities.
  • Excellent customer service and client relations skills.
  • Organizational and time management skills.
  • Great collaboration and teamwork abilities.
  • Great leadership skills.
  • Adaptable to work in a fast-paced environment.
  • Advanced data analysis and data visualization.
  • Expert inventory management.
  • Ability to use computers, software and other technology for inventory and communication purposes.
  • Understanding of the supply chain, including common obstacles and effective solutions.
  • Flexibility to work various shifts as required.
  • Flexible and willing to perform other tasks as assigned.
  • Ability to lift 60 lbs. 
Please note this job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities, and activities may change at any time with or without notice.

Work Environment

The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
 
  • Must be willing to work in a facility producing radioactive materials and requiring all employees to participate in safety programs designed to minimize potential and/or actual exposure levels.
  • Must be able to work outside of regular work hours, including off shift, weekend, and holiday work as business needs require.
  • May be required to sit or stand for long periods of 8+ hours a day while performing duties. 
  • Occasional kneeling, crouching, twisting the upper body, bending, stooping, pushing, pulling, or reaching may be required.
  • Must possess good hand-eye coordination; close attention to detail is required.
  • Must be able to work indoors and outdoors with exposure to mechanical/moving parts, hazards including radioactive, corrosive, flammable and toxic material, dust, dirt, odors, and irritants.
  • Must be willing to wear a variety of Personal Protective Equipment (PPE), including eye and hearing protection, as needed.
  • Willingness to complete safety training within allotted timeframes, and work in a team-based environment.

For information on Perspective Therapeutics, visit our website at: www.perspectivetherapeutics.com.

Perspective Therapeutics provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.

This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation, and training.
 

Perspective Therapeutics provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state, or local laws.


This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation, and training.

For information on Perspective Therapeutics, visit our website at: www.perspectivetherapeutics.com.
 
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